The First Class of Inhibitors for YEATS Domain as Potential Therapeutic Agents for Acute Leukemia

Inhibitors to block ENL–chromatin interaction, preventing downstream oncogene transcription

Therapeutic Chemicals

Novel Analogues of Teixobactin and the Synthetic Method

Total chemical synthesis of teixobactin and its analogues, offering novel, improved antibacterial compounds

Therapeutic Chemicals

OPTIClear: A Novel Tissue Clearing Agent for the Next Generation Histology

the optical properties of tissue while leaving the structural components unchanged, minimizing tissue damage

Research Tools and Methods

A New Class of Metallo-β-lactamases inhibitors Against Antibacterial Resistance

Bismuth compounds can be administered in combination with β-lactam antibiotics to treat MBL-producing bacterial infection

Therapeutic Chemicals

Palladium (II) Complexes in Anti-cancer

Chemotherapy complexes with high stability in vitro and against physiological thiols

Therapeutic Chemicals

Platinum Complexes for Anti-cancer Treatment

Platinum complexes with high cell uptake efficiency, high nuclear DNA binding efficacy and higher toxicity than cisplatin and oxaliplatin

Therapeutic Chemicals

Immuno-Oncolytic Modified Vaccinia Tian Tan Virus and Methods of Treating Cancer

Methods to induce protective antitumor T cell responses, which are normally suppressed or even absent under the tumor environment

Therapeutic Biologics

Neutrophil Elastase (NE) and Proteinase 3 (PR3) as Diagnostic Biomarkers for Autoimmune Diabetes

Antibodies and methods for early diagnosis of Type 1 diabetes by measuring elevated activity of NE and PR3

Diagnostics